Saitama, Japan


History and Structure

Center for Outcomes Research and Economic Evaluation for Health (C2H) is a department of National Institute of Public Health (NIPH), established in 2018.


C2H was established in 2018 for the academic research on cost-effectiveness evaluation, and the public roles of the official HTA process. In Japan, where public healthcare expenditure has been increasing, we evaluate the balance between the cost and outcome of healthcare technologies. The goal of our organization is to make the public healthcare system more sustainable.

How C2H Works

If a product meets the selection criteria of cost-effectiveness evaluation, the manufacturer has to prepare and submit economic data to Chuikyo committee within 9 months after selection. The analysis data will be reviewed by academic groups on behalf of C2H within 6 months. The results of reviews are submitted to Expert committee of cost-effectiveness evaluation (ECCEE), and then the price of the product is adjusted according to the incremental cost-effectiveness ratio.

Dissemination Activities

C2H activities and reports are available from our website.

Completed HTA Reports

HTA reports can be accessed from our website:

Current Projects (A Selection)

C2H plays a key role in Japanese HTA process.

Future Plans

Human resource for HTA is limited in Japan. Capacity building is needed to promote HTA.

Agency Information

Country: Japan
Description of population served: National
Size of population served (mil): 120

Contact Information

Directory/head of agency: Takashi Fukuda
Contact person: Takeru Shiroiwa

2-3-6 Minami, Wako-shi
Saitama, 351-0197 Japan
Tel: +81-48-458-6285